Andrist's stand-up is notable for his brutal takes on subjects ranging from drug use to being sexually molestated by a man who was confined to a wheelchair.
Andrist is also one of the original members of Doug Stanhope's comedy group known as The Unbookables. Other members of the Unbookables include Sean Rouse, Henry Phillips, Otto & George, James Inman, Tom Rhodes, Auggie Smith, Lynn Shawcroft, Neil Hamburger, Travis Lipski, Brendon Walsh, Joey "Coco" Diaz, Norman Wilkerson, Brett Erickson, and others.